A PHOTOELECTRIC METHOD FOR ESTIMATING INFLAMMATORY INTENSITY IN MICE AND ITS APPLICATION TO THE ANTI-INFLAMMATORY EVALUATION OF GLUCURONIC ACID DERIVATIVES

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A photoelectric method for estimating inflammatory intensity in mice and its application to the anti-inflammatory evaluation of glucuronic acid derivatives.

As is well known, intravenously administered dye extravasates at the site of inflam mation (1-4). This phenomenon has been used as one of the bases for the bioassay of experimentally induced inflammation (5-10). However, estimation of the extravasated dye either directly or by comparison to standard color chart, was not always satisfactory because of being influenced by subjective bias. Subsequ...

متن کامل

Evaluation of linoleic acid, eladic acid and palmitic acid for cytotoxicity and anti-inflammatory activities

Background and objectives: Nigella sativa seeds have shown to possess anti-inflammatory, anti-oxidant, trenquillizer, chemopreventive and anti-neoplastic effects. Besides, they areused as nutritional flavoring agents. We have investigated the protective effects of N.  sativa seeds hexane extract and active principles against methyl phenyl pyridine (MP...

متن کامل

Evaluation of Anti-Nociceptive and Anti-Inflammatory Activities of Apium graveolens L. Roots Extract in Mice

Background and objectives: Pain is an unpleasant feeling which affects the quality of life and relieving from pain is an important goal in many treatment protocols. Apium graveolens L. (celery) has been considered as sedative, analgesic, carminative, antispasmodic and diuretic in Iranian traditional medicine. The aim of present study was to evaluate the anti-n...

متن کامل

A Study of Acute and Chronic Anti-Nociceptive and Anti-Inflammatory Effects of Thiamine in Mice

Background: Thiamine (VitB1) is a vitamin with various important physiological functions and postulated therapeutic effects.  Its use as an analgesic in neuropathic pain has been undergoing in clinical settings. However, there has been little experimental investigation on this effect. In this study, anti-nociceptive and anti-inflammatory effects of thiamine were investigated in mice. Methods: T...

متن کامل

Sinapic Acid Derivatives as Potential Anti-Inflammatory Agents: Synthesis and Biological Evaluation

Transcription factor NF-κB and relevant cytokines IL-6 and IL-8 play a pivotal role in thepathogenesis of inflammation. Sinapic acid is a natural product and was demonstrated to possessanti-inflammatory activity. In this paper, we synthesized a series of sinapic acid derivativesand evaluated their anti-inflammatory effects. The result suggested that all of the targetscompounds 7a-j inhibit NF-κ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Japanese Journal of Pharmacology

سال: 1967

ISSN: 0021-5198

DOI: 10.1016/s0021-5198(19)67507-4